Webthe lethal dose of benadryl for dogs can vary depending on the size and weight of the dog. Webaccording to veterinarians, the safe dosage of benadryl for dogs is 1mg per pound of body weight every 8 hours. Webthe lethal dose (ld 50) for diphenhydramine in dogs ranges between 24 to 30 mg/kg bw by iv administration, and death has been attributed to neuromotor excitement and.

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