The reaction is favored when carried out with an unhindered substrate and a negatively. Most nucleophilic substitutions take place by the s n 2 pathway just discussed. The key to substitution and elimination reactions is to have a good leaving group, an electronegative atom or functional group that is weakly attached to carbon and.

Webdec 16, 2021 · the product of step 1, carbocation, will be the reactant of next step and is called the intermediate for s n 1 reaction. Skip to main content. Webstereochemistry of an sn1 reaction and how it relates to the sn1 mechanism.